In this guideline, WHO recommends that long-acting injectable cabotegravir (CAB-LA) may be offered as an additional HIV prevention option for people at substantial risk of HIV infection. CAB-LA is an injectable form of pre-exposure prophylaxis (PrEP) that has been shown to be highly effective at reducing...
Worldwide, people acquire more than 1 million curable sexually transmitted infections (STIs) every day. Based on prevalence data from 2009 to 2016, in 2019, WHO published estimates of new cases of chlamydia, gonorrhoea, syphilis and trichomoniasis, showing total estimated incident cases of 376.4 million ...
The primary audience for this guideline is national HIV programme managers, people living
with HIV, health-care providers and policy-makers in low- and middle-income countries. This
guideline update will be a useful resource for clinicians and should help to shape the priorities
of policy-makers in devel...
The consolidated WHO Guidelines for malaria present all of the
current WHO recommendations for malaria. These are the product
of careful evaluation following standardized methods as part of the
WHO normative processes [1]. WHO uses strictly defined
processes to assess the quality, consistency and complet...
Tuberculosis (TB) is a leading cause of death from a single infectious agent, despite being largely curable and preventable. In 2019 an estimated 2.9 million of the 10 million people who fell ill with TB were not diagnosed or reported to the World Health Organization. The Political Declaration adopted by...
Taenia solium is a zoonotic tapeworm found globally but with particularly high transmission and hyperendemnicity in parts of Latin America, South and South-East Asia and sub-Saharan Africa. Depending on its life cycle, it causes two distinct presentations in humans: taeniasis and (neuro) cysticercosis. A...
Postpartum haemorrhage (PPH) is commonly defined as a blood loss of at least 500 mL within 24 hours after birth and affects about 5% of all women giving birth around the world. Globally, nearly one quarter of all maternal deaths are associated with PPH and, in most low-income countries, it is the main ca...
WHO promotes a public health approach to programming and delivering antiretroviral therapy (ART), which has enabled access to treatment and care for people living with HIV to be scaled up in resource-limited settings.
The 2016 WHO consolidated guidelines on the use of antiretroviral drugs for treating an...
Plague has killed millions of people during the past 25 centuries, and the disease reappeared in several countries during the 1990s. Consequently, plague was categorized as a re-emerging disease. Human plague outbreaks continue to be reported, including an outbreak of pneumonic plague in Madagascar in 20...
Miller, R. E;
Leary, A;
Scott, C. L;
Serra, V;
Lord , C. J;
Bowtell, D;
Chang, D. K;
Garsed, D. W;
Jonkers, J;
Ledermann, J. A;
Nik-Zainal, S;
Ray-Coquard, I;
Shah, S. P;
Matias-Guiu, X;
Swisher, E. M;
Yates, L. R.
The European Society for Medical Oncology (ESMO) Translational Research and Precision Medicine Working Group identified that there is currently uncertainty within the oncology community surrounding the different methods for HRD testing in HGSC. To address this, a collaborative project was launched with a...
